至尊百家乐-亲朋棋牌官网-卡塔尔世界杯小组赛亚洲分组

五邑大學(xué) | ENGLISH
師資力量
鄒慶劍
瀏覽:  發(fā)布時(shí)間:2019年04月17日

基本情況

鄒慶劍,男,四川成都人?,F(xiàn)任五邑大學(xué)藥學(xué)與食品工程學(xué)院專(zhuān)任教師。

聯(lián)系方式

地址:廣東省江門(mén)市蓬江區(qū)東成村22號(hào) 五邑大學(xué)藥學(xué)與食品工程學(xué)院

郵編:529020

郵箱:[email protected]

工作經(jīng)歷

2018年5月至今,五邑大學(xué),藥學(xué)與食品工程學(xué)院,碩士生導(dǎo)師

2016年7月至2018年5月,天津天銳生物科技有限公司,研發(fā)總監(jiān)

2013年7月至2018年6月,中國(guó)科學(xué)院廣州生物醫(yī)藥與健康研究院,研究助理

教育及學(xué)習(xí)經(jīng)歷

2007年9月-2013年 6月,中國(guó)科學(xué)技術(shù)大學(xué)生命科學(xué)學(xué)院,碩士、博士

2002年9月-2006年6月,四川農(nóng)業(yè)大學(xué)生命科學(xué)學(xué)院,學(xué)士

主要研究方向

基因治療與干細(xì)胞治療,基因編輯大動(dòng)物模型構(gòu)建與疾病治療研究

發(fā)表學(xué)術(shù)論文

1. Liu, Y., Zhou, J., Lan, T., Zhou, X., Yang, Y., Li, C., Zhang, Q., Chen, M., Wei, S., Zheng, S., Cheng, L., Zheng, Y., Lai, L., and Zou, Q. (2022) Elimination of Cas9-dependent off-targeting of adenine base editor by using TALE to separately guide deaminase to target sites. Cell Discov 8, 28(通訊作者)【IF=38.1

2. Zhou, J., Liu, Y., Wei, Y., Zheng, S., Gou, S., Chen, T., Yang, Y., Lan, T., Chen, M., Liao, Y., Zhang, Q., Tang, C., Liu, Y., Wu, Y., Peng, X., Gao, M., Wang, J., Zhang, K., Lai, L., and Zou, Q. (2022) Eliminating predictable DNA off-target effects of cytosine base editor by using dual guiders including sgRNA and TALE. Mol Ther (通訊作者)【IF=12.9

3. Lan, T., Chen, H., Tang, C., Wei, Y., Liu, Y., Zhou, J., Zhuang, Z., Zhang, Q., Chen, M., Zhou, X., et al. (2023). Mini-PE, a prime editor with compact Cas9 and truncated reverse transcriptase. Mol Ther Nucleic Acids 33, 890-897. (通訊作者)【IF=10.8

4. Chen, M., Wang, X., Li, C., Lan, T., Wei, Y., Tang, C., Zhou, X., Zhou, R., Rosa, A., Zheng, X., Ang, S., Zhang, K., Zou, Q., and Lai, L. (2022) Inducible motor neuron differentiation of human induced pluripotent stem cells in vivo. Cell Prolif, e13319(通訊作者)【IF=8.7

5. Liu, Y., Yang, Y., Suo, Y., Li, C., Chen, M., Zheng, S., Li, H., Tang, C., Fan, N., Lan, T., Zhou, J., Li, Y., Wang, J., Chen, H., Zou, Q., and Lai, L. (2022) Inducible caspase-9 suicide gene under control of endogenous oct4 to safeguard mouse and human pluripotent stem cell therapy. Mol Ther Methods Clin Dev 24, 332-341(通訊作者)【IF=6.7

6. Lan, T., Zheng, Y., Suo, Y., Wei, Y., Shi, H., Yan, Q., Zhuang, Z., Chen, H., Zhang, Q., Fan, N., Zhao, Y., Ouyang, Z., Lai, C., Liu, Z., Zhou, J., Tang, C., Kim, N. H., Zou, Q., and Wang, X. (2022) Generation of pigs with humanized type II collagen by precise human COL2A1 gene knock-in. J Genet Genomics (通訊作者)【IF=5.8

7. Zheng S, Zhong H, Zhou X, Chen M, Li W, Zi Y, Chi Y, Wang J, Zheng W, Zou Q, Lai L, Tang C. (2022). Efficient and Safe Editing of Porcine Endogenous Retrovirus Genomes by Multiple-Site Base-Editing Editor. Cells.IF=7.5】(通訊作者)

8. Wu Y, Peng X, Ang S, Gao Y, Chi Y, Wang J, Tang C, Zhou X, Feng Y, Zhang K, Zou Q, Chen M. (2023). Bcl-xL Promotes the Survival of Motor Neurons Derived from Neural Stem Cells. Biology (Basel).IF=5.1】(通訊作者)

9. Zhou J, Yan Q, Tang C, Liao Y, Zhang Q, Wang X, Zhou X, Lai L, Zou Q. Development of a rabbit model of Wiskott-Aldrich syndrome. FASEB J. 2021 Feb;35(2):e21226 (通訊作者)【IF=5.8

10. Cheng, L., Zhou, X., Zheng, Y., Tang, C., Liu, Y., Zheng, S., Liu, Y., Zhou, J., Li, C., Chen, M., Lai, L., and Zou, Q. (2021) Simple and Rapid Assembly of TALE Modules Based on the Degeneracy of the Codons and Trimer Repeats. Genes (Basel) 12(通訊作者)【IF=4.5

11. Li L, Meng H, Zhang J, Liu Y, Zou Q, Gao Y, Yang H, Lai L. A tunable, rapid, and precise drug control of protein expression by combining transcriptional and post-translational regulation systems. J Genet Genomics. 2020 Nov 20;47(11):705-712. (通訊作者)【IF=5.1

12. Zou, Q., Wang, X., Liu, Y., Ouyang, Z., Long, H., Wei, S., Xin, J., Zhao, B., Lai, S., Shen, J., Ni, Q., Yang, H., Zhong, H., Li, L., Hu, M., Zhang, Q., Zhou, Z., He, J., Yan, Q., Fan, N., Zhao, Y., Liu, Z., Guo, L., Huang, J., Zhang, G., Ying, J., Lai, L., and Gao, X. (2015) Generation of gene-target dogs using CRISPR/Cas9 system. Journal of molecular cell biology 7, 580-583(第一作者)【IF=6.7

13. Wei, S., Zou, Q., Lai, S., Zhang, Q., Li, L., Yan, Q., Zhou, X., Zhong, H., and Lai, L. (2016) Conversion of embryonic stem cells into extraembryonic lineages by CRISPR-mediated activators. Scientific reports 6, 19648(通訊作者+第一作者)【IF=5.5

14. Zou, Q., Yan, Q., Zhong, J., Wang, K., Sun, H., Yi, X., and Lai, L. (2014) Direct conversion of human fibroblasts into neuronal restricted progenitors. The Journal of biological chemistry 289, 5250-5260(第一作者)【IF=4.6

參加學(xué)術(shù)會(huì)議及論文

……

申請(qǐng)及授權(quán)專(zhuān)利

1. 鄒慶劍;程令印;鄭雨齡;鄭淑文;劉玉;周小青;唐成程;陳敏;賴(lài)良學(xué);一種基于密碼子簡(jiǎn)并性的快速TALE表達(dá)載體構(gòu)建方法,2021-07-01,申請(qǐng)?zhí)枺?202110746218.1

2. 鐘慧霖;鄒清雁;劉海霞;鄒慶劍;杜少茵;梁海燕;吳志君;葉俊杰;一種嵌合抗原受體、嵌合抗原受體臍血有核細(xì)胞及應(yīng)用,2020-12-04,申請(qǐng)?zhí)枺?02011411287.9

3. 唐成程;鄒慶劍;周小青;陳敏;賴(lài)良學(xué);用于豬MBP基因敲除的sgRNA組合物及用途,2020-06-01,申請(qǐng)?zhí)枺?02010488188.4

4. 陳敏;王霞;周繼曾;陳晃耀;魏愈慧;藍(lán)婷;鄒慶劍;周小青;唐成程;張焜;周仁平;賴(lài)良學(xué);可定向誘導(dǎo)的、抗凋亡的多能干細(xì)胞及其制備方法與應(yīng)用,2019-10-22,申請(qǐng)?zhí)枺?01911005295.0

5. 周小青;賴(lài)良學(xué);鄒慶劍;唐成程;一種提高豬胚胎基因修飾純合子的方法,2020-02-18,申請(qǐng)?zhí)枺?02010100231.5

6. 唐成程;鄭淑文;鄒慶劍;鄭雨齡;李萬(wàn)勝;周小青;資崯;陳敏;賴(lài)良學(xué);識(shí)別豬PERV基因的sgRNA及其編碼DNA和應(yīng)用,2022-01-29,申請(qǐng)?zhí)枺?02210110465.7

7. 周小青;唐成程;鄒慶劍;陳敏;賴(lài)良學(xué); 一種可用于異種器官移植的供體豬的構(gòu)建方法 -2020-08-21,申請(qǐng)?zhí)枺?02010851140.5

8. 賴(lài)良學(xué);劉洋;鄒慶劍;周繼曾;周小青;楊洋;李川;劉玉;程令印;鄭雨齡;一種單堿基編輯工具TaC9-ABE及其應(yīng)用,2021-08-20,申請(qǐng)?zhí)枺?202110963044.4

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